Mix cereals, pretzels, and nuts in large roasting pan; set aside.
In small microwaveable bowl, melt butter on HIGH (about 1 minute). Stir in Worcestershire sauce, salt, garlic powder and onion powder. Gradually drizzle over cereal mixture stirring to coat evenly.
Place roasting pan in a preheated 250°F oven. Bake 1 hour, stirring every 15 minutes.
Remove from oven; cool. Store in airtight container.
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